A systematic review following PRISMA guidelines of PubMed, Embase, Web of Science, and Cochrane databases was conducted to identify randomized controlled trials (RCTs) documenting complications following PRP injections for foot and ankle pathologies. Condition studied, demographics, and complications were extracted. Complication rates and number needed to harm (NNH) were calculated, and random-effects models were generated to compare complications using odds ratios, with a p-value < 0.05 indicating significance.
Source: ScienceDirect